Side-by-side comparison

La Roche-Posay Hyalu B5 Hyaluronic Acid Serum vs SKIN1004 Madagascar Centella Ampoule

Both are serums. They share a 70% active-ingredient overlap, so the real decision is about price, texture and the supporting ingredients. Here's the side-by-side.

70%Active overlap
La Roche-Posay
Hyalu B5 Hyaluronic Acid Serum
SerumMid-rangeMorning or evening
DrynessDamaged Barrier

Two molecular weights of hyaluronic acid with panthenol and madecassoside. Designed for visible fine-line plumping on dehydrated skin — works best on damp skin sealed with moisturiser. Fragrance-free.

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SKIN1004
Madagascar Centella Ampoule
SerumBudgetMorning or evening
IrritationSensitivityRedness

A single-ingredient-led ampoule of 100% Centella asiatica extract from Madagascar. Minimalist, fragrance-free soothing for irritated or sensitised skin; not a heavy-hitting active, by design.

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The verdict

Which should you choose?

On price, the SKIN1004 Madagascar Centella Ampoule sits in the Budget tier versus Mid-range for the La Roche-Posay — so it's the more budget-led pick if the overlap is what you're after. The La Roche-Posay leans toward Damaged Barrier, Dryness. The SKIN1004 leans toward Irritation, Redness, Sensitivity.

The overlap

What they share

At 70% active overlap, these are the ingredients doing comparable work in both formulas:

Centella Asiatica
The formulation

Ingredient stacks, side by side

La Roche-Posay — top of the list

  • Aqua / Water~50–80%
  • Glycerin~5–25%
  • Propanediol~3–10%
  • Sodium Hyaluro…~2–6%
  • Hyaluronic Acid~1.5–4%
  • Panthenol~1–2%
  • Madecassoside~1–2%
  • Tromethamine~1–2%
  • Propylene Glycol~1–2%

SKIN1004 — top of the list

  • Centella Asiati…~30–70%

● marks ingredients that appear near the top of both lists. Percentages are positional estimates from INCI order, not disclosed doses.

At a glance

The specs

La Roche-PosaySKIN1004
CategorySerumSerum
Price tierMid-rangeBudget
Best forDryness, Damaged BarrierIrritation, Sensitivity, Redness
Usage notesMorning or eveningMorning or evening
Active overlap70% — Centella Asiatica
Questions

Common questions

Is the La Roche-Posay Hyalu B5 Hyaluronic Acid Serum or the SKIN1004 Madagascar Centella Ampoule better?
Neither is universally better — they share 70% active-ingredient overlap, so for the actives that drive results they're close. The SKIN1004 Madagascar Centella Ampoule is the more budget-friendly option, while the other may differ on texture, finish and supporting ingredients. Pick based on your skin's priorities rather than a single 'winner'.
What's the difference between the La Roche-Posay Hyalu B5 Hyaluronic Acid Serum and the SKIN1004 Madagascar Centella Ampoule?
Both are serums that share Centella Asiatica. Where they differ: they sit in different price tiers (Mid-range vs Budget); the La Roche-Posay targets Damaged Barrier, Dryness; the SKIN1004 targets Irritation, Redness.
Are the La Roche-Posay Hyalu B5 Hyaluronic Acid Serum and SKIN1004 Madagascar Centella Ampoule dupes for each other?
They share 70% active-ingredient overlap based on published INCI lists, so one can stand in for the other on the actives that matter — chiefly Centella Asiatica. A dupe matches the hero actives, not the full sensory experience, so expect differences in texture, fragrance and exact concentrations.
Can I use the La Roche-Posay Hyalu B5 Hyaluronic Acid Serum and SKIN1004 Madagascar Centella Ampoule together?
They both fill the serum slot in a routine, so you'd normally pick one rather than layer both. If you want to use both, treat one as your daytime option and the other for evening, and patch-test when introducing anything new.
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77% overlap

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