Side-by-side comparison

Paula's Choice Clinical 1% Retinol Treatment vs The Ordinary Retinol 1% in Squalane

Both are serums. They share a 70% active-ingredient overlap, so the real decision is about price, texture and the supporting ingredients. Here's the side-by-side.

70%Active overlap
Paula's Choice
Clinical 1% Retinol Treatment
SerumPremiumEvening only
Fine LinesPhotoaging PreventionRough Texture

A higher-strength 1% retinol treatment buffered with peptides, vitamin C and liquorice. A serious step-up retinol for experienced users targeting wrinkles and tone; introduce slowly and pair with barrier support.

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The Ordinary
Retinol 1% in Squalane
SerumBudgetEvening only
AgingRough TextureDark SpotsSensitive skinDamaged barrier

The advanced-strength option in The Ordinary's retinol ladder — oil-based, no water, stable. For users who've already tolerated 0.2% and 0.5% and are ready to escalate. Expect visible purging and dryness in the first 2–4 weeks; pair with a barrier-supporting moisturiser and strict AM SPF.

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The verdict

Which should you choose?

On price, the The Ordinary Retinol 1% in Squalane sits in the Budget tier versus Premium for the Paula's Choice — so it's the more budget-led pick if the overlap is what you're after. The Paula's Choice leans toward Fine Lines, Photoaging Prevention. The The Ordinary leans toward Aging, Dark Spots.

The overlap

What they share

At 70% active overlap, these are the ingredients doing comparable work in both formulas:

Retinol
The formulation

Ingredient stacks, side by side

Paula's Choice — top of the list

  • Aqua~50–80%
  • Cyclopentasilox…~5–25%
  • Glycerin~3–10%
  • Dimethicone~2–6%
  • Retinol~1.5–4%

The Ordinary — top of the list

  • Squalane~50–80%
  • Caprylic/Capri…~5–25%
  • Retinol1%
  • Solanum Lycope…~2–6%
  • Simmondsia Chi…~1.5–4%
  • Rosa Rubiginos…~1–2%

● marks ingredients that appear near the top of both lists. Percentages are positional estimates from INCI order, not disclosed doses.

At a glance

The specs

Paula's ChoiceThe Ordinary
CategorySerumSerum
Price tierPremiumBudget
Best forFine Lines, Photoaging Prevention, Rough TextureAging, Rough Texture, Dark Spots
Usage notesEvening onlyEvening only
Active overlap70% — Retinol
Questions

Common questions

Is the Paula's Choice Clinical 1% Retinol Treatment or the The Ordinary Retinol 1% in Squalane better?
Neither is universally better — they share 70% active-ingredient overlap, so for the actives that drive results they're close. The The Ordinary Retinol 1% in Squalane is the more budget-friendly option, while the other may differ on texture, finish and supporting ingredients. Pick based on your skin's priorities rather than a single 'winner'.
What's the difference between the Paula's Choice Clinical 1% Retinol Treatment and the The Ordinary Retinol 1% in Squalane?
Both are serums that share Retinol. Where they differ: they sit in different price tiers (Premium vs Budget); the Paula's Choice targets Fine Lines, Photoaging Prevention; the The Ordinary targets Aging, Dark Spots.
Are the Paula's Choice Clinical 1% Retinol Treatment and The Ordinary Retinol 1% in Squalane dupes for each other?
They share 70% active-ingredient overlap based on published INCI lists, so one can stand in for the other on the actives that matter — chiefly Retinol. A dupe matches the hero actives, not the full sensory experience, so expect differences in texture, fragrance and exact concentrations.
Can I use the Paula's Choice Clinical 1% Retinol Treatment and The Ordinary Retinol 1% in Squalane together?
They both fill the serum slot in a routine, so you'd normally pick one rather than layer both. If you want to use both, treat one as your daytime option and the other for evening, and patch-test when introducing anything new.
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77% overlap

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