Cell Turnover / Skin Shedding
The natural process by which the outermost dead skin cells (corneocytes) are continuously shed from the surface of the stratum corneum and replaced by new cells migrating up from the basal layer. The complete skin cell turnover cycle takes approximately 28 days in young adults, slowing to 45–60+ days in middle age and older adults. Slowed desquamation leads to a buildup of dead cells, causing dullness, rough texture, clogged pores, and reduced penetration of topical actives.
Chemical exfoliants (AHAs, BHAs) and retinoids accelerate desquamation by breaking down the desmosomes and desmoglein proteins that anchor cells together. This is the mechanism behind their texture-improving and brightening effects.
Build a routine using Skin Stacker's free AI-powered tool — decode any product, check ingredient compatibility, and get a personalised AM/PM schedule.
Open Skin Stacker →