Purine Nucleoside / FDA Anti-Wrinkle Ingredient
A naturally occurring purine nucleoside with FDA-approval as an anti-wrinkle ingredient — one of only a handful of OTC actives with this designation. Binds adenosine receptors in the dermis, stimulating fibroblast proliferation and collagen I synthesis while reducing collagen-degrading MMP activity. Statistically significant wrinkle reduction shown at 0.04%.
Topical 0.04–0.3% in serums or eye creams, AM and PM.
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